CACNA1E antibody

Catalog No. ABIN5965336

Product Details anti-CACNA1E Antibody

Target: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1E antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human CACNA1E

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CACNA1E

Target: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Alternative Name: CACNA1E (CACNA1E Products)

Synonyms: caV2.3 antibody, CACNA1E antibody, BII antibody, CACH6 antibody, CACNL1A6 antibody, Cav2.3 antibody, A430040I15 antibody, Cach6 antibody, Cacnl1a6 antibody, Cchra1 antibody, alpha1E antibody, CACHA1E antibody, calcium voltage-gated channel subunit alpha1 E antibody, calcium channel, voltage-dependent, R type, alpha 1E subunit antibody, CACNA1E antibody, cacna1e antibody, Cacna1e antibody

Background:

Synonyms: Calcium Voltage-Gated Channel Subunit Alpha1 E,Brain Calcium Channel II,CACNL1A6,CACH6,BII,Calcium Channel, Voltage-Dependent, R Type, Alpha 1E Subunit,Voltage-Dependent R-Type Calcium Channel Subunit Alpha-1E,Calcium Channel, L Type, Alpha-1 Polypeptide, Isoform 6,Calcium Voltage-Gated Channel Subunit Alpha1 Subunit E.

Background: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight:

Observed_MW: 290kDa

Calculated_MW: 254kDa/257kDa/261kDa

Gene ID: 777

UniProt: Q15878

Pathways: Carbohydrate Homeostasis