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CD8B antibody

CD8B Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5965404
  • Target See all CD8B Antibodies
    CD8B (CD8b Molecule (CD8B))
    Reactivity
    • 73
    • 30
    • 22
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 75
    • 37
    • 21
    Rabbit
    Clonality
    • 77
    • 55
    • 1
    Polyclonal
    Conjugate
    • 55
    • 17
    • 15
    • 13
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD8B antibody is un-conjugated
    Application
    • 77
    • 67
    • 44
    • 21
    • 14
    • 13
    • 13
    • 13
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human CD8B
    Isotype
    IgG
    Top Product
    Discover our top product CD8B Primary Antibody
  • Application Notes
    WB 1:200 - 1:500
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CD8B (CD8b Molecule (CD8B))
    Alternative Name
    CD8B (CD8B Products)
    Synonyms
    Cd8b antibody, Ly-3 antibody, Ly-C antibody, Lyt-3 antibody, CD8B1 antibody, LEU2 antibody, LY3 antibody, LYT3 antibody, P37 antibody, Cd8b1 antibody, CD8b molecule antibody, CD8 antigen, beta chain 1 antibody, Cd8b antibody, CD8B antibody, Cd8b1 antibody
    Background

    Synonyms: CD8b antigen,CD8 antigen beta polypeptide 1 (p37),CD8 antigen beta polypeptide 1,CD8 beta,CD8b,CD8b molecule,CD8B,CD8B1,Leu2,Ly3,LYT3,MGC119115,P37,T cell surface glycoprotein CD8 beta chain,T lymphocyte surface glycoprotein beta chain,T-cell surface glycoprotein CD8 beta chain

    Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

    Molecular Weight

    Observed_MW: 45kDa

    Calculated_MW: 20kDa/22kDa/23kDa/24kDa/25kDa/27kDa

    Gene ID
    926
    UniProt
    P10966
    Pathways
    TCR Signaling
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