MAP2K6 antibody

Catalog No. ABIN5965825

Product Details anti-MAP2K6 Antibody

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human MAP2K6

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAP2K6

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Alternative Name: MAP2K6 (MAP2K6 Products)

Synonyms: MAPKK6 antibody, MEK6 antibody, MKK6 antibody, PRKMK6 antibody, SAPKK-3 antibody, SAPKK3 antibody, Mkk6 antibody, Prkmk6 antibody, MKK3 antibody, map2k3 antibody, zMKK3 antibody, map2k6 antibody, mitogen-activated protein kinase kinase 6 antibody, mitogen-activated protein kinase kinase 6 L homeolog antibody, MAP2K6 antibody, Map2k6 antibody, map2k6 antibody, map2k6.L antibody

Background:

Synonyms: Dual specificity mitogen activated protein kinase kinase 6,Dual specificity mitogen-activated protein kinase kinase 6,MAP kinase kinase 6,MAP2K6,MAPK/ERK kinase 6,MAPKK 6,MAPKK6,MEK 6,MEK6,Mitogen Activated Protein Kinase Kinase 6,MKK 6,MKK6,MP2K6,PRKMK6,Protein kinase mitogen activated kinase 6,protein kinase,mitogen-activated,kinase 6 (MAP kinase kinase 6),SAPK kinase 3,SAPKK-3,SAPKK3,SKK3,Stress-activated protein kinase kinase 3

Background: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Molecular Weight:

Observed_MW: 38kDa

Calculated_MW: 31kDa/37kDa

Gene ID: 5608

UniProt: P52564

Pathways: MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades