ME1 antibody

Catalog No. ABIN5967412

Product Details anti-ME1 Antibody

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ME1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ME1

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ME1

Target: ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))

Alternative Name: ME1 (ME1 Products)

Synonyms: HUMNDME antibody, MES antibody, D9Ertd267e antibody, Mdh-1 antibody, Mod-1 antibody, Mod1 antibody, MOD1 antibody, ME1 antibody, zgc:153079 antibody, malic enzyme 1 antibody, malic enzyme 1, NADP(+)-dependent, cytosolic antibody, ME1 antibody, Me1 antibody, me1 antibody

Background:

Synonyms: Cytosolic malic enzyme 1,HUMNDME,Malate dehydrogenase,Malic enzyme 1,Malic enzyme 1,NADP(+) dependent,cytosolic,Malic enzyme 1,soluble,Malic enzyme,cytoplasmic,MAOX,ME1,MES,NADP dependent malic enzyme,NADP ME,NADP-dependent malic enzyme,NADP-ME,Pyruvic malic carboxylase

Background: This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Molecular Weight:

Observed_MW: 64kDa

Calculated_MW: 55kDa/64kDa

Gene ID: 4199

UniProt: P48163

Pathways: Regulation of Lipid Metabolism by PPARalpha