NQO1 antibody

Catalog No. ABIN5967456

Product Details anti-NQO1 Antibody

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NQO1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant Protein of human NQO1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Alternative Name: NQO1 (NQO1 Products)

Synonyms: zgc:77191 antibody, wu:fb63c10 antibody, nqo1 antibody, DHQU antibody, DIA4 antibody, DTD antibody, NMOR1 antibody, NMORI antibody, QR1 antibody, Dia4 antibody, AV001255 antibody, Dtd antibody, Nmo-1 antibody, Nmo1 antibody, Nmor1 antibody, Ox-1 antibody, Ox1 antibody, Qr1 antibody, NADPH-d antibody, NAD(P)H dehydrogenase, quinone 1 antibody, NAD(P)H quinone dehydrogenase 1 antibody, NAD(P)H dehydrogenase, quinone 1 L homeolog antibody, nqo1 antibody, NQO1 antibody, Bpet2092 antibody, nqo1.L antibody, Nqo1 antibody

Background:

Synonyms: Azoreductase,Cytochrome b 5 reductase,DHQU,DIA 4,DIA4,Diaphorase (NADH/NADPH) (cytochrome b 5 reductase),Diaphorase (NADH/NADPH),Diaphorase 4,Dioxin inducible 1,DT diaphorase,DT-diaphorase,DTD,Menadione reductase,NAD(P)H dehydrogenase [quinone] 1,NAD(P)H dehydrogenase quinone 1,NAD(P)H menadione oxidoreductase 1 dioxin inducible,NAD(P)H quinone dehydrogenase 1,NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1,NAD(P)H:menadione oxidoreductase 1,NAD(P)H:Quinone acceptor oxidoreductase type 1,NAD(P)H:quinone oxidoreductase 1,NAD(P)H:quinone oxireductase,NMOR 1,NMOR I,NMOR1,NMORI,NQO 1,NQO1,NQO1,Phylloquinone reductase,QR 1,QR1,Quinone reductase 1

Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight:

Observed_MW: 31kDa

Calculated_MW: 26kDa/27kDa/30kDa

Gene ID: 1728

UniProt: P15559