PLAU antibody
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- Target See all PLAU Antibodies
- PLAU (Plasminogen Activator, Urokinase (PLAU))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PLAU antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Radioimmunoassay (RIA)
- Specificity
- Recognizes human Urokinase. Does not cross-react with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, thrombin). Human whole plasma or plasma proteins do not interfere with its binding to urokinase. Binds to human HMW-scuPA (54kD), HMW-tsuPA (52kD) and LMW-scuPA (33kD) with high apparent affinity (Kd= 0.1 nM) completely inhibiting the ability of urokinase to activate plasminogen. Also inhibits the synthetic substrate S2444.
- Purification
- Affinity purified
- Immunogen
- Native human Urokinase.
- Isotype
- IgG
- Top Product
- Discover our top product PLAU Primary Antibody
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- Application Notes
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Approved: ELISA (1:5000), IHC, IHC-Fr (1:50), IHC-P (1:50), RIA, WB (1:50)
Usage: Suitable for use in RIA, ELISA, Western Blot, Dot Blot and Immunohistochemistry. Immunohistochemistry (Frozen, paraffin): 1:50. ELISA: 1:5000. Optimal dilutions should be tested by serial dilution. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Sterile distilled water
- Concentration
- Lot specific
- Buffer
- Lyophilized
- Handling Advice
- Aliquot to Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.
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- Target
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- Alternative Name
- PLAU / Urokinase / UPA (PLAU Products)
- Synonyms
- PLAU antibody, u-PA antibody, ATF antibody, BDPLT5 antibody, QPD antibody, UPA antibody, URK antibody, uPA antibody, UPAM antibody, plasminogen activator, urokinase antibody, urokinase-type plasminogen activator antibody, PLAU antibody, CpipJ_CPIJ002131 antibody, CpipJ_CPIJ006543 antibody, CpipJ_CPIJ013396 antibody, CpipJ_CPIJ013623 antibody, Plau antibody
- Background
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Name/Gene ID: PLAU
Subfamily: Serine S1
Family: Protease
Synonyms: PLAU, BDPLT5, U-PA, U-plasminogen activator, URK, Urokinase, Plasminogen activator, urinary, QPD, UPA - Gene ID
- 5328
- UniProt
- P00749
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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