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PYCARD antibody (AA 121-170)

PYCARD Reactivity: Human, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6746135
  • Target See all PYCARD Antibodies
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Binding Specificity
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-170
    Reactivity
    • 56
    • 9
    • 9
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 47
    • 7
    • 3
    Rabbit
    Clonality
    • 46
    • 11
    Polyclonal
    Conjugate
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PYCARD antibody is un-conjugated
    Application
    • 39
    • 23
    • 15
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Human PYCARD
    Predicted Reactivity
    Percent identity by BLAST analysis:
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic peptide located between aa121-170 of human PYCARD (Q9ULZ3, NP_037390). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%), Marmoset (92%), Hamster, Panda, Bat, Rabbit, Horse, Pig (85%), Rat (78%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product PYCARD Primary Antibody
  • Application Notes
    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Distilled water
    Concentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Nakashio, Fujita, Rokudai, Sato, Tsuruo: "Prevention of phosphatidylinositol 3'-kinase-Akt survival signaling pathway during topotecan-induced apoptosis." in: Cancer research, Vol. 60, Issue 18, pp. 5303-9, (2000) (PubMed).

    Auphan, DiDonato, Rosette, Helmberg, Karin: "Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis." in: Science (New York, N.Y.), Vol. 270, Issue 5234, pp. 286-90, (1995) (PubMed).

    Cordle, Donald, Read, Hawiger: "Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells." in: The Journal of biological chemistry, Vol. 268, Issue 16, pp. 11803-10, (1993) (PubMed).

    Haskill, Beg, Tompkins, Morris, Yurochko, Sampson-Johannes, Mondal, Ralph, Baldwin: "Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity." in: Cell, Vol. 65, Issue 7, pp. 1281-9, (1991) (PubMed).

  • Target
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    Alternative Name
    PYCARD / ASC (PYCARD Products)
    Synonyms
    ASC antibody, CARD5 antibody, TMS antibody, TMS-1 antibody, TMS1 antibody, 9130417A21Rik antibody, Asc antibody, TNS1 antibody, masc antibody, asc1 antibody, zAsc antibody, zgc:109874 antibody, PYD and CARD domain containing antibody, PYCARD antibody, Pycard antibody, pycard antibody
    Background
    Name/Gene ID: PYCARD
    Family: Apoptosis

    Synonyms: PYCARD, CARD5, HASC, ASC, TMS, TMS-1, PYD and CARD domain containing, TMS1
    Gene ID
    29108
    NCBI Accession
    NP_037390
    UniProt
    Q9ULZ3
    Pathways
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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