LINGO1 antibody (AA 42-240)

Catalog No. ABIN6143246

Product Details anti-LINGO1 Antibody

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Binding Specificity: AA 42-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CPPRCECSAQ DRAVLCHRKR FVAVPEGIPT ETRLLDLGKN RIKTLNQDEF ASFPHLEELE LNENIVSAVE PGAFNNLFNL RTLGLRSNRL KLIPLGVFTG LSNLTKLDIS ENKIVILLDY MFQDLYNLKS LEVGDNDLVY ISHRAFSGLN SLEQLTLEKC NLTSIPTEAL SHLHGLIVLR LRHLNINAIR DYSFKRLYR

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-240 of human LINGO1 (NP_116197.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: LINGO1 (LINGO1 Products)

Synonyms: lern1 antibody, lrrn6a antibody, unq201 antibody, DKFZp459P0736 antibody, LERN1 antibody, LRRN6A antibody, UNQ201 antibody, 4930471K13Rik antibody, AV148400 antibody, LINGO-1 antibody, Lrrn6a antibody, leucine rich repeat and Ig domain containing 1 antibody, LINGO1 antibody, lingo1 antibody, Lingo1 antibody

Background: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity.,LINGO1,LERN1,LRRN6A,UNQ201,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Neuroscience,LINGO1

Molecular Weight: 69 kDa

Gene ID: 84894

UniProt: Q96FE5