Claudin 18 antibody (AA 20-80)
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- Target See all Claudin 18 (CLDN18) Antibodies
- Claudin 18 (CLDN18)
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Binding Specificity
- AA 20-80
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Claudin 18 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GCIAATGMDM WSTQDLYDNP VTSVFQYEGL WRSCVRQSSG FTECRPYFTI LGLPAMLQAV R
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-80 of human CLDN18 (NP_057453.1).
- Isotype
- IgG
- Top Product
- Discover our top product CLDN18 Primary Antibody
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- Application Notes
- WB,1:1000 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Claudin 18 (CLDN18)
- Alternative Name
- CLDN18 (CLDN18 Products)
- Synonyms
- claudin-18 antibody, CLDN18 antibody, SFTA5 antibody, SFTPJ antibody, claudin 18 L homeolog antibody, claudin 18 antibody, cldn18.L antibody, CLDN18 antibody, Cldn18 antibody
- Background
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.,CLDN18,SFTA5,SFTPJ,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN18
- Molecular Weight
- 27 kDa
- Gene ID
- 51208
- UniProt
- P56856
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
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