MLL5/KMT2E antibody (AA 200-500)

Catalog No. ABIN6221745

Product Details anti-MLL5/KMT2E Antibody

Target: MLL5/KMT2E (MLL5) (Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5))

Binding Specificity: AA 200-500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLL5/KMT2E antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: VELYTAFQHT PTSITLTASR VSKVNDKRRK KSGEKEQHIS KCKKAFREGS RKSSRVKGSA PEIDPSSDGS NFGWETKIKA WMDRYEEANN NQYSEGVQRE AQRIALRLGN GNDKKEMNKS DLNTNNLLFK PPVESHIQKN KKILKSAKDL PPDALIIEYR GKFMLREQFE ANGYFFKRPY PFVLFYSKFH GLEMCVDART FGNEARFIRR SCTPNAEVRH EIQDGTIHLY IYSIHSIPKG TEITIAFDFD YGNCKYKVDC ACLKENPECP VLKRSSESME NINSGYETRR KKGKKDKDIS K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human KMT2E (NP_061152.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MLL5/KMT2E

Target: MLL5/KMT2E (MLL5) (Myeloid/lymphoid Or Mixed-Lineage Leukemia 5 (Trithorax Homolog) (MLL5))

Alternative Name: KMT2E (MLL5 Products)

Synonyms: HDCMC04P antibody, MLL5 antibody, 1810033J14Rik antibody, 9530077A04Rik antibody, D230038D11Rik antibody, Mll5 antibody, lysine methyltransferase 2E antibody, lysine (K)-specific methyltransferase 2E antibody, KMT2E antibody, Kmt2e antibody

Background: This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized.,KMT2E,HDCMC04P,MLL5,NKp44L,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Transcription Factors,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Stem Cells,Hematopoietic Progenitors,KMT2E

Molecular Weight: 68 kDa/98 kDa/131 kDa/180-204 kDa

Gene ID: 55904

UniProt: Q8IZD2

Pathways: Retinoic Acid Receptor Signaling Pathway, Warburg Effect