MARK1 antibody (AA 560-700)

Catalog No. ABIN6143561

Product Details anti-MARK1 Antibody

Target: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Binding Specificity: AA 560-700

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: HPIKVTLPTI KDGSEAYRPG TTQRVPAASP SAHSISTATP DRTRFPRGSS SRSTFHGEQL RERRSVAYNG PPASPSHETG AFAHARRGTS TGIISKITSK FVRRDPSEGE ASGRTDTSRS TSGEPKERDK EEGKDSKPRS L

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 560-700 of human MARK1 (NP_061120.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MARK1

Target: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Alternative Name: MARK1 (MARK1 Products)

Synonyms: MGC80341 antibody, MARK1 antibody, AW491150 antibody, B930025N23Rik antibody, Emk3 antibody, Par-1c antibody, mKIAA1477 antibody, mPar-1c antibody, MARK antibody, Par1c antibody, MAP/microtubule affinity-regulating kinase 1 S homeolog antibody, microtubule affinity regulating kinase 1 antibody, MAP/microtubule affinity-regulating kinase 1 antibody, MAP/microtubule affinity regulating kinase 1 antibody, mark1.S antibody, MARK1 antibody, mark1 antibody, Mark1 antibody

Background: Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3.,MARK1,MARK,Par-1c,Par1c,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,MARK1

Molecular Weight: 72 kDa/84 kDa/89 kDa

Gene ID: 4139

UniProt: Q9P0L2

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection