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NLRC4 antibody (AA 1-250)

NLRC4 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6144657
  • Target See all NLRC4 Antibodies
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    Binding Specificity
    • 9
    • 9
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-250
    Reactivity
    • 37
    • 15
    • 6
    • 2
    Human
    Host
    • 26
    • 9
    • 2
    Rabbit
    Clonality
    • 27
    • 10
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRC4 antibody is un-conjugated
    Application
    • 27
    • 17
    • 11
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    MNFIKDNSRA LIQRMGMTVI KQITDDLFVW NVLNREEVNI ICCEKVEQDA ARGIIHMILK KGSESCNLFL KSLKEWNYPL FQDLNGQSLF HQTSEGDLDD LAQDLKDLYH TPSFLNFYPL GEDIDIIFNL KSTFTEPVLW RKDQHHHRVE QLTLNGLLQA LQSPCIIEGE SGKGKSTLLQ RIAMLWGSGK CKALTKFKFV FFLRLSRAQG GLFETLCDQL LDIPGTIRKQ TFMAMLLKLR QRVLFLLDGY
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NLRC4 (NP_067032.3).
    Isotype
    IgG
    Top Product
    Discover our top product NLRC4 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
    Alternative Name
    NLRC4 (NLRC4 Products)
    Synonyms
    CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody
    Background
    This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.,NLRC4,AIFEC,CARD12,CLAN,CLAN1,CLANA,CLANB,CLANC,CLAND,CLR2.1,FCAS4,IPAF,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Caspases,Cell Cycle,Endocrine & Metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRC4
    Molecular Weight
    10 kDa/18 kDa/40 kDa/116 kDa
    Gene ID
    58484
    UniProt
    Q9NPP4
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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