PTPRN antibody (AA 600-889)

Catalog No. ABIN6146466

Product Details anti-PTPRN Antibody

Target: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Binding Specificity: AA 600-889

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: STGHMILAYM EDHLRNRDRL AKEWQALCAY QAEPNTCATA QGEGNIKKNR HPDFLPYDHA RIKLKVESSP SRSDYINASP IIEHDPRMPA YIATQGPLSH TIADFWQMVW ESGCTVIVML TPLVEDGVKQ CDRYWPDEGA SLYHVYEVNL VSEHIWCEDF LVRSFYLKNV QTQETRTLTQ FHFLSWPAEG TPASTRPLLD FRRKVNKCYR GRSCPIIVHC SDGAGRTGTY ILIDMVLNRM AKGVKEIDIA ATLEHVRDQR PGLVRSKDQF EFALTAVAEE VNAILKALPQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-889 of human PTPRN (NP_001186693.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRN

Target: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Alternative Name: PTPRN (PTPRN Products)

Synonyms: IA-2 antibody, IA-2/PTP antibody, IA2 antibody, ICA512 antibody, R-PTP-N antibody, mIA-A antibody, mKIAA4064 antibody, Ia-2 antibody, fc43c04 antibody, ptprn antibody, wu:fc43c04 antibody, ia-2 antibody, ia2 antibody, ica512 antibody, r-ptp-n antibody, protein tyrosine phosphatase, receptor type N antibody, protein tyrosine phosphatase, receptor type, N antibody, protein tyrosine phosphatase, receptor type, Na antibody, protein tyrosine phosphatase, receptor type N L homeolog antibody, PTPRN antibody, Ptprn antibody, ptprna antibody, ptprn.L antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.,PTPRN,IA-2,IA-2/PTP,IA2,ICA512,R-PTP-N,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,PTPRN

Molecular Weight: 96 kDa/102 kDa/105 kDa

Gene ID: 5798

UniProt: Q16849