SEMA7A antibody (AA 45-280)

Catalog No. ABIN6147525

Product Details anti-SEMA7A Antibody

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Binding Specificity: AA 45-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMA7A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QGHLRSGPRI FAVWKGHVGQ DRVDFGQTEP HTVLFHEPGS SSVWVGGRGK VYLFDFPEGK NASVRTVNIG STKGSCLDKR DCENYITLLE RRSEGLLACG TNARHPSCWN LVNGTVVPLG EMRGYAPFSP DENSLVLFEG DEVYSTIRKQ EYNGKIPRFR RIRGESELYT SDTVMQNPQF IKATIVHQDQ AYDDKIYYFF REDNPDKNPE APLNVSRVAQ LCRGDQGGES SLSVSK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 45-280 of human SEMA7A (NP_003603.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SEMA7A

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Alternative Name: SEMA7A (SEMA7A Products)

Synonyms: 2900057C09Rik antibody, CDw108 antibody, H-Sema-L antibody, M-Sema-L antibody, Semal antibody, CD108 antibody, H-SEMA-K1 antibody, JMH antibody, SEMAK1 antibody, SEMAL antibody, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antibody, semaphorin 7A (John Milton Hagen blood group) antibody, Sema7a antibody, SEMA7A antibody

Background: This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,SEMA7A,CD108,CDw108,H-SEMA-K1,H-Sema-L,JMH,SEMAK1,SEMAL,Immunology & Inflammation,CD markers,Neuroscience,Cardiovascular,Blood,SEMA7A

Molecular Weight: 73 kDa/74 kDa

Gene ID: 8482

UniProt: O75326

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size