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TLE1 antibody (AA 256-355)
TLE1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TLE1 Antibody
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Target
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TLE1
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Binding Specificity
All epitopes for TLE1 antibodies
AA 256-355
Reactivity
All reactivities for TLE1 antibodies
Human
Host
All hosts for TLE1 antibodies
Rabbit
Clonality
All clonalities for TLE1 antibodies
Polyclonal
Conjugate
All conjugates for TLE1 antibodies
This TLE1 antibody is un-conjugated
Application
All applications for TLE1 antibodies
Western Blotting (WB)
Sequence
DPSSPRASPA HSPRENGIDK NRLLKKDASS SPASTASSAS STSLKSKEMS LHEKASTPVL KSSTPTPRSD MPTPGTSATP GLRPGLGKPP AIDPLVNQAA
Cross-Reactivity
Mouse
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 256-355 of human TLE1 (NP_005068.2).
Isotype
IgG
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Discover our top product TLE1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for TLE1
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Target
TLE1
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Alternative Name
TLE1 (TLE1 Products )
Synonyms
ESG antibody, ESG1 antibody, GRG1 antibody, C230057C06Rik antibody, Estm14 antibody, Grg1 antibody, Tle4l antibody, TLE1 antibody, transducin like enhancer of split 1 antibody, transducin-like enhancer protein 1 antibody, transducin-like enhancer of split 1 antibody, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) antibody, TLE1 antibody, Smp_150080 antibody, Tle1 antibody, LOC100354911 antibody, LOC100524475 antibody, LOC100061341 antibody
Background
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.,TLE1,ESG,ESG1,GRG1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,Stem Cells,TLE1
Molecular Weight
83 kDa
Gene ID
7088
UniProt
Q04724
Pathways
WNT Signaling , SARS-CoV-2 Protein Interactome
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