UCHL1 antibody
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- Target See all UCHL1 Antibodies
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
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Reactivity
- Human, Rat, Mouse, Cow, Pig
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This UCHL1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Purpose
- Mouse Monoclonal anti-PGP 9.5 / UCHL-1 (31A3), Purified, BSA-free
- Characteristics
- This MAb reacts with a protein of 20-30 kDa, identified as PGP 9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1). Initially, PGP 9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP 9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP 9.5 gene is believed to cause a form of Parkinson's disease. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Purification
- Purified
- Immunogen
- Native UchL1 (PGP 9.5) protein from brain
- Clone
- 31A3
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product UCHL1 Primary Antibody
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- Application Notes
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Comment
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Cerebellum
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS (no BSA, no azide)
- Preservative
- Azide free
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- Target
- UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
- Alternative Name
- PGP 9.5 (UCHL-1) (UCHL1 Products)
- Synonyms
- PARK5 antibody, PGP 9.5 antibody, PGP9.5 antibody, PGP95 antibody, Uch-L1 antibody, UCH-L1 antibody, UCHL1 antibody, cb358 antibody, wu:fc55h08 antibody, park5 antibody, pgp9.5 antibody, uch-l1 antibody, MGC132191 antibody, uchl1 antibody, AW822034 antibody, C88048 antibody, R75593 antibody, UCHL-1 antibody, gad antibody, ubiquitin C-terminal hydrolase L1 antibody, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) antibody, ubiquitin C-terminal hydrolase L1 L homeolog antibody, ubiquitin carboxyl-terminal esterase L1 antibody, ubiquitin carboxy-terminal hydrolase L1 antibody, UCHL1 antibody, uchl1 antibody, uchl1.L antibody, LOC100304750 antibody, Uchl1 antibody
- Molecular Weight
- 20-30 kDa
- Gene ID
- 7345, 518731
- UniProt
- P09936
- Pathways
- Feeding Behaviour
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