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REST antibody (AA 760-1060)
REST
Reactivity: Human
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-REST Antibody
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Target
See all REST Antibodies
REST
(RE1-Silencing Transcription Factor (REST))
Binding Specificity
All epitopes for REST antibodies
AA 760-1060
Reactivity
All reactivities for REST antibodies
Human
Host
All hosts for REST antibodies
Rabbit
Clonality
All clonalities for REST antibodies
Polyclonal
Conjugate
All conjugates for REST antibodies
This REST antibody is un-conjugated
Application
All applications for REST antibodies
Immunofluorescence (IF)
Sequence
PVKIELSPPI EVVQKEPVQM ELSPPMGVVQ KEPAQREPPP PREPPLHMEP ISKKPPLRKD KKEKSNMQSE RARKEQVLIE VGLVPVKDSW LLKESVSTED LSPPSPPLPK ENLREEASGD QKLLNTGEGN KEAPLQKVGA EEADESLPGL AANINESTHI SSSGQNLNTP EGETLNGKHQ TDSIVCEMKM DTDQNTRENL TGINSTVEEP VSPMLPPSAV EEREAVSKTA LASPPATMAA NESQEIDEDE GIHSHEGSDL SDNMSEGSDD SGLHGARPVP QESSRKNAKE ALAVKAAKGD F
Cross-Reactivity
Human
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 760-1060 of human REST/NRSF (NP_001180437.1).
Isotype
IgG
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Discover our top product REST Primary Antibody
Alternatives
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Application Details
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Application Notes
IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for REST
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Target
REST
(RE1-Silencing Transcription Factor (REST))
Alternative Name
REST (REST Products )
Synonyms
NRSF antibody, XBR antibody, 2610008J04Rik antibody, AA407358 antibody, xbr antibody, nrsf antibody, rest antibody, resta antibody, REST antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, RE1-silencing transcription factor S homeolog antibody, REST antibody, Rest antibody, rest.S antibody, rest antibody, LOC615792 antibody
Background
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described,REST,NRSF,WT6,XBR,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Neurodegenerative Diseases,REST
Molecular Weight
35 kDa/36 kDa/119 kDa/121 kDa
Gene ID
5978
UniProt
Q13127
Pathways
Negative Regulation of Hormone Secretion , Regulation of Hormone Metabolic Process , Regulation of Hormone Biosynthetic Process , Chromatin Binding , Positive Regulation of Endopeptidase Activity
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