Integrin Alpha2b antibody (AA 693-993)

Catalog No. ABIN6221333

Product Details anti-Integrin Alpha2b Antibody

Target: Integrin Alpha2b (CD41)

Binding Specificity: AA 693-993

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALSNVEGFER LICNQKKENE TRVVLCELGN PMKKNAQIGI AMLVSVGNLE EAGESVSFQL QIRSKNSQNP NSKIVLLDVP VRAEAQVELR GNSFPASLVV AAEEGEREQN SLDSWGPKVE HTYELHNNGP GTVNGLHLSI HLPGQSQPSD LLYILDIQPQ GGLQCFPQPP VNPLKVDWGL PIPSPSPIHP AHHKRDRRQI FLPEPEQPSR LQDPVLVSCD SAPCTVVQCD LQEMARGQRA MVTVLAFLWL PSLYQRPLDQ FVLQSHAWFN VSSLPYAVPP LSLPRGEAQV WTQLLRALEE R

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 693-993 of human CD41/CD41/ITGA2B (NP_000410.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B (CD41 Products)

Synonyms: AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody

Background: This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.,ITGA2B,BDPLT16,BDPLT2,CD41,CD41B,GP2B,GPIIb,GT,GTA,HPA3,PPP1R93,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Blood,ITGA2B

Molecular Weight: 103 kDa/109 kDa/113 kDa

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex