TNK2 antibody (pTyr284)

Catalog No. ABIN6225608

Product Details anti-TNK2 Antibody

Target: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Binding Specificity: pTyr284

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNK2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DHYVM

Cross-Reactivity: Human

Characteristics: Phosphorylated Antibodies

Immunogen: A synthetic phosphorylated peptide around Y284 of human TNK2 (NP_005772.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TNK2

Target: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Alternative Name: TNK2 (TNK2 Products)

Synonyms: ACK antibody, ACK-1 antibody, ACK1 antibody, p21cdc42Hs antibody, AW552477 antibody, Ack antibody, Cdgip antibody, Pyk1 antibody, ack1 antibody, ackb antibody, tnk2 antibody, tnk2b antibody, wu:fj16g04 antibody, zgc:154019 antibody, tyrosine kinase non receptor 2 antibody, tyrosine kinase, non-receptor, 2 antibody, tyrosine kinase, non-receptor, 1 antibody, TNK2 antibody, Tnk2 antibody, tnk1 antibody

Background: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.,TNK2,ACK,ACK-1,ACK1,p21cdc42Hs,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,EGF,Protein phosphorylation,TNK2

Molecular Weight: 60 kDa/114 kDa/119 kDa

Gene ID: 10188

UniProt: Q07912