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METTL14 antibody (AA 2-36)

METTL14 Reactivity: Human, Mouse WB, IHC (p), IF Host: Rabbit Polyclonal RB55130 unconjugated
Catalog No. ABIN6243447
  • Target See all METTL14 Antibodies
    METTL14 (Methyltransferase Like 14 (METTL14))
    Binding Specificity
    • 15
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-36
    Reactivity
    • 27
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 26
    • 1
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This METTL14 antibody is un-conjugated
    Application
    • 21
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Predicted Reactivity
    B
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This METTL14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the human region of human METTL14.
    Clone
    RB55130
    Isotype
    Ig Fraction
    Top Product
    Discover our top product METTL14 Primary Antibody
  • Application Notes
    WB: 1:2000. IHC-P: 1:250
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    METTL14 (Methyltransferase Like 14 (METTL14))
    Alternative Name
    METTL14 (METTL14 Products)
    Synonyms
    RGD1304822 antibody, G430022H21Rik antibody, mKIAA1627 antibody, zgc:77296 antibody, methyltransferase like 14 antibody, methyltransferase like 14 L homeolog antibody, Mettl14 antibody, mettl14.L antibody, METTL14 antibody, mettl14 antibody
    Background
    N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.
    Molecular Weight
    52150
    UniProt
    Q9HCE5
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