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CD14 antibody (FITC)

GMP Grade CD14 Reactivity: Human FACS Host: Mouse Monoclonal M5E2 FITC
Catalog No. ABIN6253089
  • Target See all CD14 Antibodies
    CD14
    Reactivity
    • 223
    • 45
    • 30
    • 29
    • 28
    • 28
    • 25
    • 24
    • 22
    • 18
    • 15
    • 14
    • 10
    • 9
    • 8
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 183
    • 59
    • 16
    • 3
    • 1
    Mouse
    Clonality
    • 202
    • 60
    Monoclonal
    Conjugate
    • 109
    • 29
    • 21
    • 15
    • 12
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD14 antibody is conjugated to FITC
    Application
    • 184
    • 93
    • 56
    • 47
    • 42
    • 40
    • 20
    • 15
    • 14
    • 13
    • 13
    • 12
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Characteristics
    The clone M5E2, a mouse monoclonal antibody, specifically recognizes a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The expression of CD14 is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. M5E2 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes. M5E2 has crossreactivity with various species including non-human rhesus macaques.
    Purification
    Purified
    Purity
    >95 %
    Grade
    GMP Grade
    Immunogen
    Full-length human CD14 protein
    Clone
    M5E2
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD14 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    CD14
    Alternative Name
    CD14 (CD14 Products)
    Synonyms
    CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
    Background
    The clone 26ic, a mouse monoclonal antibody, reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)- anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. 26ic binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.
    UniProt
    P08571
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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