GFER antibody (C-Term)
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- Target See all GFER Antibodies
- GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))
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Binding Specificity
- C-Term
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GFER antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- ALR Antibody detects endogenous levels of total ALR.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ALR, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GFER Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- GFER (Growth Factor, Augmenter of Liver Regeneration (GFER))
- Alternative Name
- GFER (GFER Products)
- Synonyms
- ALR antibody, ERV1 antibody, HERV1 antibody, HPO antibody, HPO1 antibody, HPO2 antibody, HSS antibody, Alr antibody, growth factor, augmenter of liver regeneration antibody, growth factor, augmenter of liver regeneration L homeolog antibody, GFER antibody, Gfer antibody, gfer.L antibody
- Background
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Description: Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.
Gene: GFER
- Molecular Weight
- 23-25 kDa
- Gene ID
- 2671
- UniProt
- P55789
- Pathways
- SARS-CoV-2 Protein Interactome
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