CDCA8 antibody

Catalog No. ABIN6260693

Product Details anti-CDCA8 Antibody

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: CDCA8 Antibody detects endogenous levels of total CDCA8

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CDCA8

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Alternative Name: CDCA8 (CDCA8 Products)

Synonyms: BOR antibody, BOREALIN antibody, DasraB antibody, MESRGP antibody, Bor antibody, Borr antibody, CG4454 antibody, Dmel\\CG4454 antibody, dBor antibody, borea antibody, Dasra-B antibody, GgDasraB antibody, 4831429J16Rik antibody, AU044747 antibody, Borealin antibody, D4Ertd421e antibody, bor antibody, dasrab antibody, borealin antibody, cdca8l antibody, sb:cb373 antibody, zgc:101607 antibody, cell division cycle associated 8 antibody, borealin-related antibody, Borealin antibody, cell division cycle associated 8 L homeolog antibody, CDCA8 antibody, borr antibody, borea antibody, Cdca8 antibody, cdca8.L antibody, cdca8 antibody

Background:

Description: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Gene: CDCA8

Molecular Weight: 31kDa

Gene ID: 55143

UniProt: Q53HL2

Pathways: Cell Division Cycle, M Phase