TLE3 antibody (Internal Region)

Catalog No. ABIN6265593

Product Details anti-TLE3 Antibody

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: TLE3 Antibody detects endogenous levels of total TLE3.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TLE3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TLE3

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Alternative Name: TLE3 (TLE3 Products)

Synonyms: TLE3 antibody, ESG antibody, ESG1 antibody, Xesg1 antibody, esg2 antibody, esg3 antibody, grg2 antibody, grg3 antibody, hst18976 antibody, tle3 antibody, xgrg3 antibody, ESG3 antibody, GRG3 antibody, HsT18976 antibody, Esp3 antibody, 2610103N05Rik antibody, Grg3a antibody, Grg3b antibody, mKIAA1547 antibody, transducin like enhancer of split 3 antibody, transducin like enhancer of split 2 antibody, transducin-like enhancer of split 3 antibody, TLE3 antibody, tle2 antibody, Tle3 antibody

Background:

Description: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).

Gene: TLE3

Molecular Weight: 83 kDa

Gene ID: 7090

UniProt: Q04726

Pathways: SARS-CoV-2 Protein Interactome