UBA2 antibody (C-Term)

Catalog No. ABIN6265834

Product Details anti-UBA2 Antibody

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Uba2 Antibody detects endogenous levels of total Uba2.

Predicted Reactivity: Pig,Bovine,Horse,Sheep

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Uba2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for UBA2

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Alternative Name: UBA2 (UBA2 Products)

Synonyms: ATSAE2 antibody, EMB2764 antibody, EMBRYO DEFECTIVE 2764 antibody, F3K23.23 antibody, F3K23_23 antibody, SUMO-ACTIVATING ENZYME 2 antibody, SUMO-activating enzyme 2 antibody, ARX antibody, SAE2 antibody, AA986091 antibody, Arx antibody, Sae2 antibody, UBA1 antibody, Ubl1a2 antibody, Uble1b antibody, sae2 antibody, sae2-B antibody, uba2-a antibody, uba2-b antibody, uble1b-B antibody, sae2b antibody, uble1b antibody, wu:fi17g06 antibody, zgc:66354 antibody, SUMO1 activating enzyme subunit 2 antibody, SUMO-activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 antibody, ubiquitin-like modifier activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 L homeolog antibody, MICPUN_63834 antibody, MICPUCDRAFT_36729 antibody, SAE2 antibody, UBA2 antibody, Uba2 antibody, uba2.L antibody, uba2 antibody

Background:

Description: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Gene: UBA2

Molecular Weight: 71kDa

Gene ID: 10054

UniProt: Q9UBT2