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Lysine (K)-Specific Methyltransferase 2B (KMT2B) (C-Term) antibody

KMT2B Reactivity: Human, Mouse, Rat ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6266015
  • Target See all Lysine (K)-Specific Methyltransferase 2B (KMT2B) Antibodies
    Lysine (K)-Specific Methyltransferase 2B (KMT2B)
    Binding Specificity
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 15
    • 3
    • 2
    Rabbit
    Clonality
    • 17
    • 3
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 11
    • 6
    • 5
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    WBP7 Antibody detects endogenous levels of total WBP7.
    Predicted Reactivity
    Bovine,Horse,Sheep,Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human WBP7, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product KMT2B Primary Antibody
  • Application Notes
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Lysine (K)-Specific Methyltransferase 2B (KMT2B)
    Alternative Name
    KMT2B (KMT2B Products)
    Synonyms
    HRX2 antibody, MLL1B antibody, MLL2 antibody, MLL4 antibody, TRX2 antibody, WBP7 antibody, lysine methyltransferase 2B antibody, KMT2B antibody
    Background

    Description: Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.

    Gene: KMT2B

    Molecular Weight
    294kDa
    Gene ID
    9757
    UniProt
    Q9UMN6
    Pathways
    Warburg Effect
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