XRCC4 antibody (Internal Region)
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- Target See all XRCC4 Antibodies
- XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This XRCC4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- XRCC4 Antibody detects endogenous levels of total XRCC4.
- Predicted Reactivity
- Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human XRCC4, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product XRCC4 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
- Alternative Name
- XRCC4 (XRCC4 Products)
- Synonyms
- zgc:73312 antibody, MGC81443 antibody, homolog of human DNA ligase iv-binding protein XRCC4 antibody, 2310057B22Rik antibody, AW413319 antibody, AW545101 antibody, X-ray repair cross complementing 4 antibody, X-ray repair complementing defective repair in Chinese hamster cells 4 antibody, X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog antibody, DNA ligase IV-binding protein antibody, XRCC4 antibody, xrcc4 antibody, xrcc4.L antibody, Xrcc4 antibody
- Background
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Description: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Gene: XRCC4
- Molecular Weight
- 38kDa
- Gene ID
- 7518
- UniProt
- Q13426
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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