NR1D1 antibody (Internal Region)

Catalog No. ABIN6283471

Product Details anti-NR1D1 Antibody

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Binding Specificity: AA 350-430, Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1D1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Rabbit polyclonal to Rev-erbα.

Specificity: Rev-erbα Polyclonal Antibody detects endogenous levels of Rev-erbα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Rev-erbalpha

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
ELISA 1:10000

Comment:

Widely expressed. Expressed at high levels in the liver, adipose tissue, skeletal muscle and brain. Also expressed in endothelial cells (ECs), vascular smooth muscle cells (VSMCs) and macrophages. Expression oscillates diurnally in the suprachiasmatic nucleus (SCN) of the hypothalamus as well as in peripheral tissues. Expression increases during the differentiation of pre-adipocytes into mature adipocytes. Expressed at high levels in some squamous carcinoma cell lines.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for NR1D1

Target: NR1D1 (Nuclear Receptor Subfamily 1, Group D, Member 1 (NR1D1))

Alternative Name: Rev-erbalpha (NR1D1 Products)

Synonyms: MGC82865 antibody, MGC82881 antibody, Eip75B antibody, EAR1 antibody, THRA1 antibody, THRAL antibody, ear-1 antibody, hRev antibody, A530070C09Rik antibody, R75201 antibody, REV-ERBAALPHA antibody, nuclear receptor subfamily 1 group D member 1 L homeolog antibody, nuclear receptor subfamily 1, group d, member 1 antibody, nuclear receptor subfamily 1 group D member 1 antibody, nuclear receptor subfamily 1, group D, member 1 antibody, nr1d1.L antibody, nr1d1 antibody, NR1D1 antibody, Nr1d1 antibody

Molecular Weight: 67 kDa

Gene ID: 9572

UniProt: P20393

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha