Calnexin antibody (AA 520-600)

Catalog No. ABIN6284356

Product Details anti-Calnexin Antibody

Target: Calnexin (CANX)

Binding Specificity: AA 520-600

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Calnexin is a protein encoded by the CANX gene which is approximately 67,5 kDa. Calnexin is localised to the endoplasmic reticulum membrane. It is involved in class I MHC mediated antigen processing and presentation, assembly of viral components at the budding site and the calnexin/calreticulin cycle. It is a calcium-binding, endoplasmic reticulum-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It also plays a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Calnexin is expressed in the nervous system, liver, skin, blood and lung. Mutations in the CANX gene may result in Frey syndrome and orbital melanoma. STJ91978 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Calnexin protein.

Specificity: Calnexin Polyclonal Antibody detects endogenous levels of Calnexin protein.

Characteristics: Rabbit polyclonal to Calnexin.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Calnexin around the non-phosphorylation site of S583.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C, and avoid repeat freeze-thaw cycles.

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: Calnexin (CANX Products)

Synonyms: CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody

Molecular Weight: 90 kDa

Gene ID: 821

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis