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HIF3A antibody (Internal Region)

HIF3A Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6286917
  • Target See all HIF3A Antibodies
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    Binding Specificity
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 29
    • 16
    • 13
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 4
    • 1
    Rabbit
    Clonality
    • 31
    • 1
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIF3A antibody is un-conjugated
    Application
    • 19
    • 11
    • 10
    • 5
    • 2
    • 2
    Western Blotting (WB), ELISA
    Purpose
    Rabbit polyclonal to HIF-3α.
    Specificity
    HIF-3α Polyclonal Antibody detects endogenous levels of HIF-3α protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from human HIF-3alpha.
    Isotype
    IgG
    Top Product
    Discover our top product HIF3A Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    ELISA 1:20000
    Comment

    Expressed in vascular cells (at protein level) . Expressed in kidney . Expressed in lung epithelial cells . Expressed in endothelial cells (venous and arterial cells from umbilical cord and aortic endothelial cells) and in vascular smooth muscle cells (aorta) . Strongly expressed in the heart, placenta, and skeletal muscle, whereas a weak expression profile was found in the lung, liver, and kidney . Expressed weakly in cell renal cell carcinoma (CC-RCC) compared to normal renal cells . Expression is down-regulated in numerous kidney tumor cells compared to non tumor kidney tissues . Isoform 2 is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas and in numerous cancer cell lines . Isoform 3 and isoform 4 are weakly expressed in heart, placenta, lung, liver, skeletal muscle and pancreas . Isoform 4 is expressed in fetal tissues, such as heart, brain, thymus, lung, liver, skeletal kidney and spleen . Isoform 3 is weakly expressed in fetal tissues, such as liver and kidney .

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Target
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    Alternative Name
    HIF-3alpha (HIF3A Products)
    Synonyms
    HIF-3A antibody, IPAS antibody, MOP7 antibody, PASD7 antibody, bHLHe17 antibody, Ipas antibody, NEPAS antibody, Mop7 antibody, HIF3A antibody, hypoxia inducible factor 3 alpha subunit antibody, hypoxia inducible factor 3, alpha subunit antibody, HIF3A antibody, Hif3a antibody
    Molecular Weight
    72 kDa
    UniProt
    Q9Y2N7
    Pathways
    Warburg Effect
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