QPRT antibody

Catalog No. ABIN6290813

Product Details anti-QPRT Antibody

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QPRT antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human QPRT

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for QPRT

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Alternative Name: QPRT (QPRT Products)

Synonyms: ECK0108 antibody, JW0105 antibody, VF2184 antibody, QPRTase antibody, 2410027J01Rik antibody, AI647766 antibody, quinolinate phosphoribosyltransferase antibody, nicotinate-nucleotide pyrophosphorylase antibody, nicotinate-nucleotide diphosphorylase antibody, carboxylating antibody, ECs0113 antibody, nadC antibody, VP2522 antibody, STY0167 antibody, BJE04_RS13210 antibody, QPRT antibody, Qprt antibody

Background: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.

Molecular Weight: 30.846 kDa

Gene ID: 23475

UniProt: Q15274