ITPR1 antibody

Catalog No. ABIN6293225

Product Details anti-ITPR1 Antibody

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPR1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ITPR1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Widely expressed

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ITPR1

Target: ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))

Alternative Name: ITPR1 (ITPR1 Products)

Synonyms: D6Pas2 antibody, ENSMUSG00000072853 antibody, Gm10429 antibody, IP3R1 antibody, InsP3R antibody, Ip3r antibody, Itpr-1 antibody, P400 antibody, Pcp-1 antibody, Pcp1 antibody, opt antibody, I145TR antibody, InsP3R1 antibody, INSP3R1 antibody, IP3R antibody, SCA15 antibody, SCA16 antibody, SCA29 antibody, inositol 1,4,5-trisphosphate receptor type 1 antibody, inositol 1,4,5-trisphosphate receptor 1 antibody, inositol 1,4,5-trisphosphate receptor, type 1 antibody, ITPR1 antibody, Itpr1 antibody

Background: This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Molecular Weight: 313.929 kDa

Gene ID: 3708

UniProt: Q14643

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma