FDFT1 antibody (N-Term)

Catalog No. ABIN629705

Product Details anti-FDFT1 Antibody

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDFT1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: FDFT1 antibody was raised against the N terminal of FDFT1

Purification: Purified

Immunogen: FDFT1 antibody was raised using the N terminal of FDFT1 corresponding to a region with amino acids HSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRM

Application Details

Application Notes: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

FDFT1 Blocking Peptide, catalog no. 33R-3852, is also available for use as a blocking control in assays to test for specificity of this FDFT1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of FDFT1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for FDFT1

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Alternative Name: FDFT1 (FDFT1 Products)

Synonyms: FDFT1 antibody, DKFZp459C1712 antibody, SQS antibody, SS antibody, DGPT antibody, ERG9 antibody, fdft1 antibody, farnesyl-diphosphate farnesyltransferase 1 antibody, squalene synthase antibody, farnesyl diphosphate farnesyl transferase 1 antibody, FDFT1 antibody, fdft1 antibody, LOC100560926 antibody, Fdft1 antibody

Background: FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

Molecular Weight: 48 kDa (MW of target protein)

Pathways: Regulation of Lipid Metabolism by PPARalpha