ELISA: 0.5-2 µg/mL, Inhibition: 0.2-0.4 µg/mL, WB: 0.1-0.2 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Concentration
Lot specific
Buffer
Lyophilized from PBS, pH 7.2.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
IL33 is a proinflammatory protein that shares structural and functional characteristics with the IL1 cytokine family. It binds and signals through the IL1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL33 induces production of TH2 cell related cytokines, including IL4, IL5 and IL13, and exerts multiple inflammation related bioactivities.