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SPHK1 antibody
SPHK1
Reactivity: Human
IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPHK1 Antibody
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Target
See all SPHK1 Antibodies
SPHK1
(Sphingosine Kinase 1 (SPHK1))
Reactivity
All reactivities for SPHK1 antibodies
Human
Host
All hosts for SPHK1 antibodies
Rabbit
Clonality
All clonalities for SPHK1 antibodies
Polyclonal
Conjugate
All conjugates for SPHK1 antibodies
This SPHK1 antibody is un-conjugated
Application
All applications for SPHK1 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
Affinity chromatography purified
Immunogen
SPHK1 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
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Application Details
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Application Notes
IHC-P: 10 µg/mL Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
Target Details for SPHK1
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Target
SPHK1
(Sphingosine Kinase 1 (SPHK1))
Alternative Name
SPHK1 (SPHK1 Products )
Synonyms
CG1747 antibody, Dmel\\CG1747 antibody, SK1 antibody, Sphk1 antibody, SPHK1 antibody, F18E5.160 antibody, F18E5_160 antibody, sphingosine kinase 1 antibody, SPHK antibody, 1110006G24Rik antibody, Sk1 antibody, Spk1 antibody, Sphingosine kinase 1 antibody, sphingosine kinase 1 antibody, sphingosine kinase 1 L homeolog antibody, Sk1 antibody, SPHK1 antibody, sphk1.L antibody, Sphk1 antibody
Background
Sphingosine kinase 1 phosphorylates sphingosine to sphingosine-1-phosphate (S1P) SK1 is normally a cytosolic protein but is recruited to membranes rich in phosphatidate (PA), a product of Phospholipase D (PLD). Various stimuli increase cellular levels of sphingosine-1-phosphate (SPP) by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine.
Pathways
VEGF Signaling
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