GRM2 antibody
-
- Target See all GRM2 Antibodies
- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GRM2 antibody is un-conjugated
-
Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Affinity chromatography purified
- Immunogen
- GRM2 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
- Top Product
- Discover our top product GRM2 Primary Antibody
-
-
- Application Notes
-
IHC-P: 4 µg/mL
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
-
- Concentration
- Lot specific
- Buffer
- Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.
-
- Target
- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
- Alternative Name
- GRM2 (GRM2 Products)
- Synonyms
- GLUR2 antibody, GPRC1B antibody, MGLUR2 antibody, mGlu2 antibody, 4930441L02Rik antibody, Gprc1b antibody, mGluR2 antibody, mGluR7 antibody, glutamate metabotropic receptor 2 antibody, glutamate receptor, metabotropic 2 antibody, GRM2 antibody, Grm2 antibody
- Background
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The receptors in group II, including mGluRs 2 and 3, and group III, including mGluRs 4, 6, 7, and 8, (with some exceptions) prevent the formation of cyclic adenosine monophosphate, or cAMP, by activating a G protein that inhibits the enzyme adenylyl cyclase, which forms cAMP from ATP.
- Pathways
- cAMP Metabolic Process, Dicarboxylic Acid Transport
-