MUC1 antibody (pTyr1229)
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- Target See all MUC1 Antibodies
- MUC1 (Mucin 1 (MUC1))
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Binding Specificity
- pTyr1229
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MUC1 antibody is un-conjugated
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Application
- Dot Blot (DB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This MUC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1229 of human MUC1.
- Clone
- RB15190
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MUC1 Primary Antibody
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- Application Notes
- DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 6 months
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- Target
- MUC1 (Mucin 1 (MUC1))
- Alternative Name
- MUC1 (MUC1 Products)
- Synonyms
- CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
- Background
- MUC1 is a member of the mucin family and a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
- Molecular Weight
- 122102
- Gene ID
- 4582
- NCBI Accession
- NP_001018016, NP_001018017, NP_001037855, NP_001037856, NP_001037857, NP_001037858, NP_001191214, NP_001191215, NP_001191216, NP_001191217, NP_001191218, NP_001191219, NP_001191220, NP_00
- UniProt
- P15941
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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