INSC antibody (AA 410-437)

Catalog No. ABIN2842997

Product Details anti-INSC Antibody

Target: INSC (Inscuteable Homolog (INSC))

Binding Specificity: AA 410-437

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This INSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the Central region of human INSC.

Clone: RB22206

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for INSC

Target: INSC (Inscuteable Homolog (INSC))

Alternative Name: INSC (INSC Products)

Synonyms: 3830422K02Rik antibody, C730020D23 antibody, RGD1311379 antibody, INSC, spindle orientation adaptor protein antibody, inscuteable homolog (Drosophila) antibody, INSC antibody, Insc antibody

Background: In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).

Molecular Weight: 63469

Gene ID: 387755

NCBI Accession: NP_001027024, NP_001036001, NP_001265242, NP_001265243, NP_001265244, NP_001265245

UniProt: Q1MX18