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PTGS2 antibody (AA 363-391)
PTGS2
Reactivity: Human
WB, IF, IHC (p)
Host: Rabbit
Polyclonal
RB17409
unconjugated
Product Details anti-PTGS2 Antibody
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Target
See all PTGS2 Antibodies
PTGS2
(Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
Binding Specificity
All epitopes for PTGS2 antibodies
AA 363-391
Reactivity
All reactivities for PTGS2 antibodies
Human
Host
All hosts for PTGS2 antibodies
Rabbit
Clonality
All clonalities for PTGS2 antibodies
Polyclonal
Conjugate
All conjugates for PTGS2 antibodies
This PTGS2 antibody is un-conjugated
Application
All applications for PTGS2 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PTGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-391 amino acids from the Central region of human PTGS2.
Clone
RB17409
Isotype
IgG
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Discover our top product PTGS2 Primary Antibody
Alternatives
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Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-PTGS2 antibody (ABIN655500)
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Peng, You, Zhang, Xi, Zhang, Dong, Cai, Wang, Zhang, Zhou, Gao, Wen : "Predictive value of APAF-1 and COX-2 expression in pathologic complete response to neoadjuvant chemoradiotherapy for patients with locally advanced rectal adenocarcinoma. " in: Oncotarget , Vol. 7 , Issue 23 , pp. 35233-40 , (2018 ) (PubMed ).
Target Details for PTGS2
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Target
PTGS2
(Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
Alternative Name
PTGS2 (PTGS2 Products )
Synonyms
COX-2 antibody, COX2 antibody, GRIPGHS antibody, PGG/HS antibody, PGHS-2 antibody, PHS-2 antibody, hCox-2 antibody, Cox-2 antibody, Pghs2 antibody, TIS10 antibody, Cox2 antibody, cox-2 antibody, CEF147 antibody, PGHS2 antibody, PHSII antibody, cox2 antibody, gripghs antibody, pgg/hs antibody, pghs-2 antibody, phs-2 antibody, PTGS2 antibody, hcox-2 antibody, fj02a10 antibody, ptgs2 antibody, unp1239 antibody, wu:fj02a10 antibody, zCOX-2 antibody, si:dkey-97o5.6 antibody, prostaglandin-endoperoxide synthase 2 antibody, prostaglandin G/H synthase 2 antibody, prostaglandin-endoperoxide synthase 2S homeolog antibody, prostaglandin-endoperoxide synthase 2a antibody, prostaglandin-endoperoxide synthase 2b antibody, PTGS2 antibody, Ptgs2 antibody, LOC100136456 antibody, ptgs2.S antibody, ptgs2 antibody, ptgs2a antibody, ptgs2b antibody
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Molecular Weight
68996
Gene ID
5743
NCBI Accession
NP_000954
UniProt
P35354
Pathways
Brown Fat Cell Differentiation , Positive Regulation of fat Cell Differentiation
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