SPHK1 antibody
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- Target See all SPHK1 Antibodies
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPHK1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human SPHK1
- Isotype
- IgG
- Top Product
- Discover our top product SPHK1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IHC 1:50 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SPHK1 (Sphingosine Kinase 1 (SPHK1))
- Alternative Name
- SPHK1 (SPHK1 Products)
- Synonyms
- CG1747 antibody, Dmel\\CG1747 antibody, SK1 antibody, Sphk1 antibody, SPHK1 antibody, F18E5.160 antibody, F18E5_160 antibody, sphingosine kinase 1 antibody, SPHK antibody, 1110006G24Rik antibody, Sk1 antibody, Spk1 antibody, Sphingosine kinase 1 antibody, sphingosine kinase 1 antibody, sphingosine kinase 1 L homeolog antibody, Sk1 antibody, SPHK1 antibody, sphk1.L antibody, Sphk1 antibody
- Background
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Synonyms: SK 1,SK1,Sphingosine kinase 1,SPHK 1,SPHK,Sphk1,SPHK1,SPK ,SPK 1
Background: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 55kDa
Calculated_MW: 42kDa/43kDa/51kDa
- Gene ID
- 8877
- UniProt
- Q9NYA1
- Pathways
- VEGF Signaling
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