TYMS antibody
-
- Target See all TYMS Antibodies
- TYMS (Thymidylate Synthetase (TYMS))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TYMS antibody is un-conjugated
-
Application
- Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human TYMS (NP_001062.1).
- Isotype
- IgG
- Top Product
- Discover our top product TYMS Primary Antibody
-
-
- Application Notes
- IF 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- TYMS (Thymidylate Synthetase (TYMS))
- Alternative Name
- TYMS (TYMS Products)
- Synonyms
- FN1 antibody, ECK2823 antibody, JW2795 antibody, ts antibody, Ts antibody, HST422 antibody, TMS antibody, TS antibody, thymidylate synthetase antibody, contains intron in T4 phage antibody, ThyE antibody, thymidylate synthase antibody, thymidylate synthetase L homeolog antibody, TYMS antibody, thyA antibody, td antibody, thyE antibody, DDA3937_RS04960 antibody, tyms.L antibody, XBJ1_RS15770 antibody, EAMY_RS20680 antibody, Tyms antibody
- Target Type
- Viral Protein
- Background
- Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.
- Molecular Weight
-
Observed_MW: 36kDa
Calculated_MW: 26kDa/31kDa/35kDa
- Gene ID
- 7298
- UniProt
- P04818
- Pathways
- Mitotic G1-G1/S Phases
-