COL11A2 antibody
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- Target See all COL11A2 Antibodies
- COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COL11A2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human COL11A2
- Isotype
- IgG
- Top Product
- Discover our top product COL11A2 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))
- Alternative Name
- COL11A2 (COL11A2 Products)
- Synonyms
- col11a2 antibody, MGC89039 antibody, COL11A2 antibody, RING3 antibody, DFNA13 antibody, DFNB53 antibody, FBCG2 antibody, HKE5 antibody, PARP antibody, STL3 antibody, collagen, type XI, alpha 2 antibody, collagen type XI alpha 2 chain antibody, bromodomain containing 2 antibody, col11a2 antibody, COL11A2 antibody, BRD2 antibody, Col11a2 antibody
- Background
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Synonyms: COBA2,COL11A2,Collagen alpha 2(XI),Collagen alpha-2(XI) chain,Collagen type XI alpha 2,Collagen XI a2,DAQB-79P13.8,DFNA13,DFNB53,FBCG2,HGNC:2187,HKE5,PARP,Pro a2 chain of collagen type XI,STL3
Background: This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
- Molecular Weight
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Observed_MW: 150kDa
Calculated_MW: 31kDa/159-171kDa
- Gene ID
- 1302
- UniProt
- P13942
- Pathways
- RTK Signaling, Sensory Perception of Sound, Chromatin Binding
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