GIGYF2 antibody

Catalog No. ABIN6567319

Product Details anti-GIGYF2 Antibody

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIGYF2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human GIGYF2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GIGYF2

Target: GIGYF2 (GRB10 Interacting GYF Protein 2 (GIGYF2))

Alternative Name: GIGYF2 (GIGYF2 Products)

Synonyms: GIGYF2 antibody, TNRC15 antibody, GYF2 antibody, PARK11 antibody, PERQ2 antibody, PERQ3 antibody, 2610016F01Rik antibody, A830080H02Rik antibody, AI852361 antibody, AW259676 antibody, BC006835 antibody, Tnrc15 antibody, mKIAA0642 antibody, fb57e02 antibody, im:6911549 antibody, wu:fb57e02 antibody, zgc:111944 antibody, GRB10 interacting GYF protein 2 antibody, GRB10 interacting GYF protein 2 S homeolog antibody, GIGYF2 antibody, Gigyf2 antibody, gigyf2 antibody, gigyf2.S antibody

Background:

Synonyms: gigyf2,GRB10 interacting GYF protein 2,GRB10-interacting GYF protein 2,GYF domain containing 2,GYF2,PARK11,Parkinson disease (autosomal recessive early onset) 11,PERQ amino acid rich, with GYF domain 2,PERQ amino acid rich, with GYF domain 3,PERQ amino acid-rich with GYF domain-containing protein 2,Perq2,PERQ2,PERQ3,TNRC15,Trinucleotide repeat containing 15,Trinucleotide repeat-containing gene 15 protein

Background: This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 180kDa

Calculated_MW: 148kDa/149kDa/150kDa/152kDa

Gene ID: 26058

UniProt: Q6Y7W6

Pathways: Feeding Behaviour, SARS-CoV-2 Protein Interactome