TCEB2 antibody
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- Target See all TCEB2 Antibodies
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCEB2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human TCEB2
- Isotype
- IgG
- Top Product
- Discover our top product TCEB2 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IP 1:20 - 1:50
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
- Alternative Name
- TCEB2 (TCEB2 Products)
- Synonyms
- 0610040H15Rik antibody, cb162 antibody, wu:fb47e08 antibody, ELOB antibody, SIII antibody, elongin B antibody, Elob antibody, elob antibody, ELOB antibody
- Background
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Synonyms: EloB,ELOB,Elongin 18 kDa subunit,Elongin B,Elongin-B,RNA polymerase II transcription factor SIII p18 subunit,RNA polymerase II transcription factor SIII subunit B,SIII,SIII p18,TCEB 2,Tceb2,Transcription elongation factor B (SIII) polypeptide 2,Transcription elongation factor B polypeptide 2
Background: This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
- Molecular Weight
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Observed_MW: 16kDa
Calculated_MW: 13kDa/17kDa
- Gene ID
- 6923
- UniProt
- Q15370
- Pathways
- SARS-CoV-2 Protein Interactome
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