TCEB2 antibody

Catalog No. ABIN6567909

Product Details anti-TCEB2 Antibody

Target: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purification: Affinity purification

Immunogen: Recombinant protein of human TCEB2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IP 1:20 - 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TCEB2

Target: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Alternative Name: TCEB2 (TCEB2 Products)

Synonyms: 0610040H15Rik antibody, cb162 antibody, wu:fb47e08 antibody, ELOB antibody, SIII antibody, elongin B antibody, Elob antibody, elob antibody, ELOB antibody

Background:

Synonyms: EloB,ELOB,Elongin 18 kDa subunit,Elongin B,Elongin-B,RNA polymerase II transcription factor SIII p18 subunit,RNA polymerase II transcription factor SIII subunit B,SIII,SIII p18,TCEB 2,Tceb2,Transcription elongation factor B (SIII) polypeptide 2,Transcription elongation factor B polypeptide 2

Background: This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.

Molecular Weight:

Observed_MW: 16kDa

Calculated_MW: 13kDa/17kDa

Gene ID: 6923

UniProt: Q15370

Pathways: SARS-CoV-2 Protein Interactome