TPT1 antibody

Catalog No. ABIN6567912

Product Details anti-TPT1 Antibody

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPT1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human TPT1 (NP_003286.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TPT1 (TPT1 Products)

Synonyms: HRF antibody, TCTP antibody, p02 antibody, Trt antibody, p21 antibody, p23 antibody, TPT1 antibody, TCT1 antibody, tctp antibody, fa28a02 antibody, id:ibd2078 antibody, wu:fa28a02 antibody, PCHK23 antibody, hrf antibody, MGC79720 antibody, Tpt1 antibody, translationally controlled tumor protein antibody, CG4800 antibody, Dmel\\CG4800 antibody, dTCTP antibody, Tctp antibody, tumor protein, translationally-controlled 1 antibody, tumor protein, translationally-controlled 1 L homeolog antibody, translationally-controlled tumor protein antibody, translationally controlled tumor protein antibody, translationally controlled tumor-like protein antibody, Translationally controlled tumor protein antibody, translationally-controlled tumor protein homolog antibody, P23 tumor protein-like antibody, TPT1 antibody, Tpt1 antibody, tpt1 antibody, tpt1.L antibody, LOC711798 antibody, TCTP antibody, LOC548038 antibody, Tctp antibody, LOC108708523 antibody, LOC109404863 antibody, LOC105389397 antibody, LOC102577554 antibody

Background: This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 20kDa

Calculated_MW: 15kDa/19kDa

Gene ID: 7178

UniProt: P13693

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling