UIMC1 antibody
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- Target See all UIMC1 Antibodies
- UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UIMC1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human UIMC1
- Isotype
- IgG
- Top Product
- Discover our top product UIMC1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))
- Alternative Name
- UIMC1 (UIMC1 Products)
- Synonyms
- UIMC1 antibody, RAP80 antibody, X2HRIP110 antibody, 9430016E08Rik antibody, D330018D10Rik antibody, D630032M02Rik antibody, RIP110 antibody, Rxrip110 antibody, RGD1307009 antibody, ubiquitin interaction motif containing 1 antibody, UIMC1 antibody, Uimc1 antibody
- Background
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Synonyms: BRCA1-A complex subunit RAP80,Nuclear zinc finger protein RAP80,OTTHUMP00000161441,OTTHUMP00000223372,OTTHUMP00000223374,RAP80,Receptor associated protein 80,Receptor-associated protein 80,Retinoid X receptor interacting protein 110,Retinoid x receptor interacting protein,Retinoid X receptor-interacting protein 110,RIP110,Rxrip110,Ubiquitin interaction motif containing 1,Ubiquitin interaction motif containing protein 1,Ubiquitin interaction motif-containing protein 1,UIMC1,UIMC1,X2HRIP110
Background: This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 90kDa
Calculated_MW: 17kDa/38kDa/61kDa/70kDa/79kDa
- Gene ID
- 51720
- UniProt
- Q96RL1
- Pathways
- DNA Damage Repair, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus
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