POT1 antibody
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- Target See all POT1 Antibodies
- POT1 (Protection of Telomeres 1 (POT1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POT1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human POT1
- Isotype
- IgG
- Top Product
- Discover our top product POT1 Primary Antibody
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- Application Notes
- WB 1:200 - 1:2000 IHC 1:50 - 1:200
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- POT1 (Protection of Telomeres 1 (POT1))
- Alternative Name
- POT1 (POT1 Products)
- Synonyms
- HPOT1 antibody, POT1 antibody, DKFZp469P1825 antibody, pot1 antibody, 1500031H18Rik antibody, AI851169 antibody, Pot1 antibody, Pot1a antibody, protection of telomeres 1 antibody, protection of telomeres 1 L homeolog antibody, protection of telomeres 1A antibody, POT1 antibody, pot1.L antibody, Pot1a antibody, Pot1 antibody
- Background
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Synonyms: DKFZP586D211,hPot 1,hPot1,POT 1,POT1,POT1 like telomere end-binding protein,POT1 protection of telomeres 1 homolog,POT1-like telomere end-binding protein,POTE1,Protection of telomeres 1,Protection of telomeres 1 homolog (S. pombe),Protection of telomeres protein 1
Background: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
- Molecular Weight
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Observed_MW: 75kDa
Calculated_MW: 60kDa/71kDa
- Gene ID
- 25913
- UniProt
- Q9NUX5
- Pathways
- Cell Division Cycle, Telomere Maintenance
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