EPOR antibody
-
- Target See all EPOR Antibodies
- EPOR (Erythropoietin Receptor (EPOR))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This EPOR antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human EPOR (NP_000112.1).
- Isotype
- IgG
- Top Product
- Discover our top product EPOR Primary Antibody
-
-
- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Alternative Name
- EPOR (EPOR Products)
- Synonyms
- EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
- Background
- This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
- Molecular Weight
-
Observed_MW: 53kDa
Calculated_MW: 26kDa/35kDa/55kDa
- Gene ID
- 2057
- UniProt
- P19235
- Pathways
- JAK-STAT Signaling
-