BRIP1 antibody

Catalog No. ABIN6570721

Product Details anti-BRIP1 Antibody

Target: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human BRIP1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BRIP1

Target: BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1 (BRIP1))

Alternative Name: BRIP1 (BRIP1 Products)

Synonyms: MGC68622 antibody, BRIP1 antibody, fancj antibody, si:ch211-158l18.1 antibody, BACH1 antibody, FANCJ antibody, OF antibody, 3110009N10Rik antibody, 8030460J03Rik antibody, Bach1 antibody, FACJ antibody, Fancj antibody, BRCA1 interacting protein C-terminal helicase 1 antibody, BRCA1 interacting protein C-terminal helicase 1 L homeolog antibody, Brip1 antibody, brip1.L antibody, BRIP1 antibody, brip1 antibody

Background:

Synonyms: ATP dependent RNA helicase BRIP1,ATP-dependent RNA helicase BRIP1,BACH 1,BRAC 1 Associated C Terminal Helicase 1,BRCA 1 Interacting Protein 1,BRCA1 binding helicase like protein BACH1,BRCA1 interacting protein C terminal helicase 1,BRCA1-associated C-terminal helicase 1,BRCA1-interacting protein 1,BRCA1-interacting protein C-terminal helicase 1,BRCA1/BRCA2 associated helicase 1,BRIP 1,BRIP1,FANCJ,FANCJ,Fanconi anemia group J protein,FLJ90232,MGC126521,MGC126523,OF,Protein FACJ

Background: The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations.

Molecular Weight:

Observed_MW: 145kDa

Calculated_MW: 112kDa/140kDa

Gene ID: 83990

UniProt: Q9BX63

Pathways: DNA Damage Repair