XPC antibody
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- Target See all XPC Antibodies
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This XPC antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human XPC (NP_004619.3).
- Isotype
- IgG
- Top Product
- Discover our top product XPC Primary Antibody
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- Application Notes
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
- Alternative Name
- XPC (XPC Products)
- Synonyms
- RAD4 antibody, XP3 antibody, XPCC antibody, XPC complex subunit, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group C antibody, XPC antibody, Xpc antibody
- Background
- This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
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Observed_MW: 130kDa
Calculated_MW: 15kDa/101kDa/105kDa
- Gene ID
- 7508
- UniProt
- Q01831
- Pathways
- p53 Signaling, DNA Damage Repair
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